KNOCK'D | SCIENCE
Acute Melatonin Administration in Humans Impairs Glucose Tolerance in Both the Morning and EveningSignificant Findings:"Acute melatonin administration in humans impairs glucose tolerance in both the morning and evening. When administering melatonin, the proximity to meal timing may need to be...
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Significant Findings:"Chronic sleep loss is a potent catabolic stressor, increasing the risk of metabolic dysfunction and loss of muscle mass and function. These acute changes may represent mechanistic precursors driving the metabolic dysfunction and body composition changes associated with chronic sleep...
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Significant Findings:"Following magnesium treatment, PLMS associated with arousals (PLMS-A) decreased significantly (17+7 vs 7±7 events per hour of total sleep time, p<0.05). PLMS without arousal were also moderately reduced (PLMS per hour of total sleep time 33+16 vs 21±23, p=0.07)....
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Significant Findings:"dietary magnesium supplementation brought about statistically significant increases in sleep time (P = 0.002), sleep efficiency (P = 0.03), concentration of serum renin (P < 0.001), and melatonin (P = 0.007). Also resulted in significant decrease of ISI score (P = 0.006), sleep onset...
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Significant Findings:"These results indicate that magnolol increased NREM and REM sleep via the GABAA receptor."Abstract:"Magnolol (6,6′,7,12-tetramethoxy-2,2′-dimethyl-1-beta-berbaman, C18H18O2), an active ingredient of the bark of Magnolia officinalis, has been reported to exert potent anti-epileptic effects via the GABAA receptor. The receptor also mediates sleep in...
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