KNOCK'D | SCIENCE
Significant Findings:"GABA/l-theanine mixture (100/20 mg/kg) showed a decrease in sleep latency (20.7 and 14.9%) and an increase in sleep duration (87.3 and 26.8%)"Abstract:" γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter and it is well established that activation of GABAA receptors favours...
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Significant Findings:"GABA significantly shortened sleep latency and increased the total non-rapid eye movement (non-REM) sleep time."Abstract:"The effects of γ-aminobutyric acid (GABA) on sleep and its levels in blood after oral administration were investigated in humans. A randomized, single-blind, placebo-controlled crossover-designed...
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Significant Findings:"Accordingly, glycine exposure increased (P < 0.05) the rate of protein synthesis (by 20–80%) and inhibited (P < 0.05) the rate of protein degradation (by 15–30%)"Abstract:"The regulation of protein turnover in skeletal muscle is essential for the maintenance of integrity, growth,...
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Significant Findings:"exogenous glycine promotes sleep via peripheral vasodilatation through the activation of NMDA receptors in the SCN shell."Abstract:"The use of glycine as a therapeutic option for improving sleep quality is a novel and safe approach. However, despite clinical evidence of...
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Significant Findings:" The decline in the core body temperature might be a mechanism underlying glycine’s effect on sleep, as the onset of sleep is known to involve a decrease in the core body temperature."Abstract:"Glycine is a non-essential amino acid that has...
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